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陈裕明
职  称: 教授(博士生导师) \

所属部门: 医学统计与流行病学系

电子邮件:   chenyum@mail.sysu.edu.cn ; chenym08@gmail.com

现任职务:  

研究方向(主要研究领域)


1. 营养因素与慢性疾病(骨质疏松、心脑血管疾病、糖尿病、肥胖等)
2. 慢性疾病的危险因素及防制措施研究
  主要研究:广州居民营养与健康队列研究;对象:约4000名40-75岁社区居民;设计:前瞻性队列研究,2008-2010年建立队列,每3年随访1次;研究因素:营养及相关因素;结局:骨密度、颈动脉超声、脂肪肝、MetS、体脂、肌肉量等;样本收集:血、尿和粪便。


学术简历

医学博士(香港中文大学)
医学硕士(华中科技大学,原同济医科大学)
预防医学学士(中南大学,原湖南医科大学)

  香港中文大学博士,中山大学统流系流行病学方向教授,兼任广东省营养学会副理事长、中国营养学会理事、中华预防医学会科技奖评审委员会委员等。教育部“新世纪优秀人才计划”获得者。主持国家自然科学基金面上项目4项,中山大学5010(50项10年)项目,以及其他课题多项。在JCEM, Am J Epidemiol, Am J Clin Nutr, Heart, Br J Cancer, Osteoporos Int, Bone, Int J Obes, Sci Rep, Int J Cardiol等国际著名期刊发表SCI论文共110篇(总IF约430,被SCI论文引用1880余次, RG指数 41),其中第一或通信作者论文55篇,最高被引频次133次。中文论文50余篇。主要研究方向为营养膳食等暴露因素与代谢性疾病(骨质疏松、动脉硬化、代谢综合征、脂肪肝、肥胖及少肌症等)的流行病学研究。 

社会兼职

1.  中国营养学会 理事
2.  广东省营养学会 副理事长
3.  中国营养学会 微量元素专业委员会 委员
4.  中华预防医学会 中华预防医学科学奖评审委员会 委员
5.  中国抗癌协会营养支持与治疗专业委员会 委员
6.  广东省营养学会 妇幼专业委员会 副主任委员

主要承担或参与的课题(5-6项代表性课题)

1. 膳食、血浆及红细胞脂肪酸与中老年人动脉粥样硬化关系的6年前瞻性研究. 国家自然科学基金, 2014.8;No. 81472965;主持人
2. 膳食模式、炎性因子、氧化应激及其相关基因对中老年居民骨质疏松影响的前瞻性研究。国家自然科学基金,2012.8;No. 81273049, 主持人。
3. 膳食抗氧化剂、抗氧化酶、氧化应激及相关基因对妇女髋骨骨折的交互作用。国家自然科学基金, 2010.8;No. 81072299;主持人
4. 候选基因及膳食模式对妇女髋骨骨折的交互作用。国家自然科学基金,2008.9,No. 30872100,主持人
5 营养膳食及基因多态性对动脉粥样硬化影响的前瞻性研究。国家自然科学基金 重点项目, 2011.9;No. 81130052. 第二
6. 青少年、哺乳期妇女、绝经期妇女钙需要量研究。国家十一五支撑项目“我国重点人群铁、钙需要和膳食应用研究(No. 2008BAI58B02)”分题。批准年月:2008.11,起止年月,2009.1-2010.12。Co-PI
7. 常见慢病的患病与发病趋势及其影响因素的前瞻性研究。中山大学“临床医学研究5010计划”。No. 2007032;2007.11-2015.10。主持人
8. 托菲尔婴儿配方奶粉和金领冠呵护婴儿配方奶粉的临床喂养效果研究。内蒙古伊利集团公司。2015.9~2017.12. 主持人
9. KMS卫生巾/护垫使用效果研究。广东景兴卫生用品有限公司。2013.10~2016.10,主持人
11. 奶及其制品摄入量对中老年人骨流失影响的前瞻性研究. 中国营养学会营养科研基金—伊利营养与健康研究基金. 2014.2;主持人。
12. 餐饮行为及膳食模式对中老年社区居民动脉粥样硬化剂及代谢综合征影响的前瞻性研究. 中国红十字会--中国肯德基餐饮健康基金。 2013.12,主持人。
13. 中老年妇女骨质疏松相关膳食模式与膳食质量指数研究。 达能营养科学基金。2012.12,主持人。


近期发表的主要文章(可以限定在近五年)

第一或通信作者论文(55篇),  * 通信作者
1.  Wang C, Lin XL, Fan YY, Liu YT, Zhang XL, Lu YK, Xu CH, Chen YM*. Diet quality scores and risk of nasopharyngeal carcinoma in Chinese adults: a case-control study. Nutrients  2016 Feb 25;8(3). pii: E112. doi: 10.3390/nu8030112
2.  Huang BX, Zhu YY, Tan XY, Lan QY, Li CL, Chen YM *, Hui-lian Zhu*. Serum Betaine is Inversely Associated with Low Lean Mass Mainly in Men in a Chinese Middle-aged and Elderly Community-dwelling Population. Br J Nutr.   2016 Mar 9. Accept.
3.  Cao Y, Wang C, Guan K, Xu Y, Su YX*, Chen YM*. Association of magnesium in serum and urine with carotid intima-media thickness and serum lipids in middle-aged and elderly Chinese: a community-based cross-sectional study. Eur J Nutr 2016 Feb;55(1):219-26. 
4.  Kang H, Chen YM*,  Han G, Huang H, Chen WQ, Wang X, Zhu YY, Xiao SM*.  Associations of Age, BMI, and Years of Menstruation with Proximal Femur Strength in Chinese Postmenopausal Women: A Cross-Sectional Study. Int J Environ Res Public Health. 2016 Jan 23;13(2). pii: E157. doi: 10.3390/ijerph13020157
5.  Chen YM, Liu Y, Zhou RF, Chen XL, Wang C, Tan XY, Wang LJ, Zheng RD, Zhang HW, Ling WH,  Zhu HL*. Associations of gut-flora-dependent metabolite trimethylamine-N-oxide, betaine and choline with non-alcoholic fatty liver disease in adults. Sci Rep  2016 Jan 8;6:19076. 
6.  Zhang ZQ, Cao WT, Liu J, Cao Y, Su YX*, Chen YM*.  Greater serum carotenoid concentration associated with higher bone mineral density in Chinese adults. Osteoporos Int. 2016 Jan 11. [Epub ahead of print]. DOI: 10.1007/s00198-015-3425-2
7.  Shi WQ, Liu J, Cao Y, Zhu YY, Guan K, Chen YM*. Association of dietary and serum vitamin E with bone mineral density in middle-aged and elderly Chinese adults: A cross-sectional study. Br J Nutr.   2016 Jan;115(1):113-20. 
8.  Zeng FF, Liu YT, Lin XL, Fan YY, Zhang XL, Xu CH, Chen YM*. Folate, vitamin B6, vitamin B12, and methionine intake and risk of nasopharyngeal carcinoma in Chinese adults: A matched case-control study. Br J Nutr.  2016 Jan;115(1):121-8. 
9.  Zeng FF, Xie HL, Fan F, Xue WQ, Wu BH, Zhu HL, Chen YM*. Association of dietary fat intake with the risk of hip fractures in an elderly Chinese population: A matched case-control study. Geriatr Gerontol Int 2015 Oct;15(10):1171-8. 
10.  Cao Y, Wang C, Liu J, Liu ZM, Ling WH, Chen YM*. Greater serum carotenoid levels associated with lower prevalence of nonalcoholic fatty liver disease in Chinese adults. Sci Rep  2015 Jul, 5,12951.
11.  Chen GD, Zhu YY, Cao Y, Liu J, Shi WQ, Liu ZM, Chen YM*. Association of dietary consumption and serum levels of vitamin A and β-carotene with bone mineral density in Chinese adults. Bone. May 28, 2015; 79: 110–115.  
12.  Dai XW, Chen YM*, Zeng FF, Sun LL, Chen CG, Su YX*. Association between n-3 polyunsaturated fatty acids in erythrocytes and metabolic syndrome in Chinese men and women. Eur J Nutr 2015 May 3. [Epub ahead of print], DOI: 10.1007/s00394-015-0912-3
13.  Lu MS, Fang YJ, Pan ZZ, Zhong X, Zheng MC, Chen YM*, Zhang CX*. Choline and Betaine Intake and Colorectal Cancer Risk in Chinese Population: A Case-Control Study. PLoS One. 2015 Mar 18;10(3):e0118661.
14.  Chen YM, Liu Y, Liu YH, Wang X, Guan K, Zhu HL*. Higher serum concentrations of betaine rather than choline is associated with better profiles of DXA-derived body fat and fat distribution in Chinese adults. Int J obes  2015 Mar;39(3):465-71. 
15.  Ye YB, Chen AL, Lu W, Zhuo SY, Liu J, Guan JH, Deng WP, Fang S, Li YB*, Chen YM*. Daidzein and genistein fail to improve glycemic control and insulin sensitivity in Chinese women with impaired glucose regulation: A double-blind, randomized, placebo-controlled trial. Mol Nutr Food Res  2015 Feb;59(2):240-9. 
16.  Liu J, Shi WQ, Cao Y, He LP, Guan K, Ling WH, Chen YM*. Higher serum carotenoid concentrations associated with a lower prevalence of the metabolic syndrome in middle-aged and elderly Chinese adults. Br J Nutr 2014 Dec;112(12):2041–2048.
17.  Sun LL, Li BL, Xie HL, Fan F, Yu WZ, Wu BH, Xue WQ, Chen YM*. Dietary intake of antioxidative nutrients and risk of hip fracture in elderly Chinese: a case-control study. Br J Nutr 2014 Oct 28, 112(10): 1706–1714.
18.  Zhang ZQ, He LP, Liu YH, Guan K, Su YX*, Chen YM*. Association between dietary intake of flavonoid and bone mineral density in middle aged and elderly Chinese women and men. Osteoporos Int 2014 Oct;25(10):2417-25. 
19.  Liu J, Sun LL, He LP, Ling WH, Liu ZM, Chen YM*. Associations of soy food consumption with cardiometabolic disturbances and carotid intima-media thickness in Chinese adults.. Nutr Metab Cardiovasc Dis 2014 Oct;24(10):1097-104. 
20.  Zhang ZQ, Liu YH, Xu Y, Dai XW, Ling WH, Su YX*, Chen YM*. The validity of the body adiposity index in predicting percentage body fat and cardiovascular risk factors among Chinese. Clin Endocrinol 2014 Sep;81(3):356-62. 
21.  Zeng FF, Sun LL, Liu YH, Xu Y, Guan K, Ling WH, Chen YM*. Higher Erythrocyte n–3 PUFAs Are Associated with Decreased Blood Pressure in Middle-Aged and Elderly Chinese Adults. J Nutr 2014 Aug;144(8):1240-6. 
22.  Zhang ZQ, He LP, Xie XY, Ling WH, Deng J, Su YX*, Chen YM*. Association of simple anthropometric indices and body fat with early atherosclerosis in Chinese adults. PLoS ONE  2014 Aug 4;9(8):e104361. 
23.  Zeng FF, Xue WQ, Cao WT, Wu BH, Xie HL, Fan F, Zhu HL*, Chen YM*. Diet-quality scores and risk of hip fractures in elderly urban Chinese in Guangdong, China: a case–control study. Osteoporos Int 2014 Aug;25(8):2131-41. 
24.  Wang CY, Chen ZW, Zang T, Liu J, Chen SH, Liu SH, Han LY, Hui ZH, Chen YM*. Elevated Plasma Homocysteine Level is Associated with Ischemic Stroke in Chinese Essential Hypertensive Patients. Eur J Intern Med 2014 Jul;25(6):538-44. 
25.  Zhang ZQ, Ma XM, Huang ZW, Yang XG, Chen YM*, Su YX*. Effects of milk salt supplementation on bone mineral gain in pubertal Chinese adolescents: A 2-year randomized, double-blind, controlled, dose–response trial. Bone  2014 May; 65: 69–76. 
26.  Xu Y, Zeng FF, He LP, Ling WH, Chen WQ, Chen YM*. Comparison of predictive value of cardiometabolic indices for subclinical atherosclerosis in Chinese adults. PLoS ONE  2014 Apr 1;9(4):e93538. 
27.  Zeng FF, Xu CH, Liu YT, Fan YY, Lin XL, Lu YK, Zhang CX, Chen YM*. Choline and betaine intakes are associated with reduced risk of nasopharyngeal carcinoma in adults: a case-control study. Br J Cancer 2014 Feb 4;110(3):808-16.
28.  Zhang ZQ, Ho SC, Chen ZQ, Zhang CX, Chen YM*.  Reference values of bone mineral density and prevalence of osteoporosis in Chinese adults. Osteoporos Int 2014 Feb;25(2):497-507.
29.  Dai XW, Zhang B, Wang P, Chen CG, Chen YM*, Su YX*. Erythrocyte membrane n-3 fatty acid levels and carotid atherosclerosis in Chinese men and women. Atherosclerosis 2014 Jan;232(1):79-85. 
30.  Liu J, Zeng FF, Liu ZM, Zhang CX, Ling WH, Chen YM*. Effect of blood triglyceride on cardiovascular and all-cause mortality: A systematic review and meta-analysis of 61 prospective studies. Lipids Health Dis  2013 October 29; 2013, 12:159.  
31.  Liu YT, Fan YY, Xu CH, Lin XL, Lu YK, Zhang XL, Zhang CX, Chen YM*. Habitual consumption of soy products and risk of nasopharyngeal carcinoma in Chinese adults: a case-control study. PLoS ONE 2013 October;8(10):e77822.
32.  Zhang ZQ, Deng J, He LP, Ling WH, Su YX*, Chen YM*. Comparison of various anthropometric and body fat indices in identifying cardiometabolic disturbances in Chinese men and women. PLoS ONE 2013 Aug 12;8(8):e70893. 
33.  Zeng FF, Fan F, Xue WQ, Xie HL, Wu BH, Tu SL, Ouyang WF, Chen YM*. The association of red meat, poultry, and egg consumption with risk of hip fractures in elderly Chinese: a case-control study. Bone 2013 October; 56(2):242–248.
34.  Xie HL, Wu BH, Xue WQ, He MG, Fan F, Ouyang WF, Tu SL, Zhu HL, Chen YM*.  Greater intake of fruit and vegetables is associated with lower risk of osteoporosis-related hip fractures in elderly Chinese: a 1:1 matched case-control study. Osteoporos Int  2013 Nov;24(11):2827-36.
35.  Liu YH , Xu Y, Wen YB, Guan K, Ling WH, He LP, Su YX*, Chen YM*. Association of weight-adjusted body fat and fat distribution with bone mineral density in middle-aged Chinese adults: A cross-sectional study. PLoS ONE 2013 May 20;8(5):e63339.
36.  Zeng FF, Wu BH, Fan F, Xie HL, Xue WQ, Zhu HL, Chen YM*. Dietary patterns and the risk of hip fractures in elderly Chinese: A matched case-control study. J Clin Endocrinol Metab 2013 Jun;98(6):2347-55. 
37.  Fan F, Xue W-Q, Wu B-H, He M-G, Xie H-L, Ouyang WF, TU SL, Chen YM*. Higher fish intake is associated with a lower risk of hip fractures in Chinese nen and women: A matched case-control study. PLoS ONE 2013; 8(2):  e56849.
38.  Li JJ, Huang ZW, Wang RQ, Ma XM, Zhang ZQ, Liu Z, Chen YM*, Su YX* Fruit and vegetable intake and bone mass in Chinese adolescents, young and postmenopausal women.  Public Health Nutr. 2013 Jan;16(1):78-86. )
39.  Zhang CX, Chen YM*, Chen WQ, Su YX, Wang CL, Wu JN. Food group intake among adolescents in Guangzhou city compared with the Chinese dietary guidelines. Asia Pac J Clin Nutr 2012;21(3):450-6. 
40.  Wang P, Chen YM*, He LP, Chen CG, Zhang B, Xue WQ, Su YX*. Association of natural intake of dietary plant sterols with carotid intima–media thickness and blood lipids in Chinese adults: a cross-section study. PLoS ONE. 2012; 7(3): e32736. 
41.  Liu YT, Dai JJ, Xu CH, Lu YK, Fan YY, Zhang XL, Zhang CX, Chen YM*. Greater intake of fruit and vegetables is associated with lower risk of nasopharyngeal carcinoma in Chinese adults: a case-control study. Cancer Causes Control. 2012 Apr;23(4):589-99. 
42.  Ye YB, Wang ZL, Zhuo SY, Lu W, Liao HF, Verbruggen MA, Fang S, Mai HY,  Chen YM*, Su YX*. Soy germ isoflavones improve menopausal symptoms but have no effect on blood lipids in early postmenopausal Chinese women: a randomized placebo-controlled trial. Menopause. 2012 Jul;19(7):791-798. 
43.  Liu Z, Qiu L, Chen YM *, Su YX *. Effect of milk and calcium supplementation on bone density and bone turnover in pregnant Chinese women: a randomized controlled trail. Arch Gynecol Obstet. 2011 Feb;283(2):205-11. 
44.  He LP, Tang XY, Ling WH, Chen WQ, Chen YM*. Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: a meta-analysis of longitudinal studies. Heart. 2010;96:339-346. (IF 6.0, Times Cited: 43) 
45.  Chen YM, Ho SC*, Lam SS. Higher sea fish intake is associated greater bone mass and lower osteoporosis risk in postmenopausal Chinese women. Osteoporos Int. 2010 Jun;21(6):939-46 (IF 4.039)(Times Cited: 12)
46.   Liu J, Ho SC, Su YX, Chen WQ, Zhang CX, Chen YM*. Effect of long-term intervention of soy isoflavones on bone mineral density in women: A meta-analysis of randomized controlled trials. Bone 2009 May;44(5):948-53.  (IF 3.823) (Times Cited: 39) (Q1)
47.  Wu JN, Ho SC, Zhou C, Ling WH, Chen WQ, Wang CL, Chen YM*. Coffee consumption and risk of coronary heart diseases: A meta-analysis of 21 prospective cohort studies. Int J Cardiol. 2009; 137: 216-225.  (IF 6.2) (Times Cited: 46)
48.  Li X, He GP, Zhang B, Chen YM*, Su YX*. Interactions of interleukin-6 gene polymorphisms with calcium intake and physical activity on bone mass in Chinese pre-menarche girls. Osteoporos Int 2008  Nov;19(11):1629-37. (IF 4.9)(Times Cited: 5) (Q1)
49.  Zhang B, Chen YM*, Huang LL, Zhou XX, Chen CG, Ye YB, Su YX*. Greater habitual soyfood consumption is associated with decreased carotid intima-media thickness and better plasma lipids in Chinese middle-aged adults. Atherosclerosis 2008 June; 198(2): 403-411. (Times Cited: 14)
50.  Wang CL, Tang XY, Chen WQ, Su YX, Zhang CX, Chen YM*. Association of Estrogen Receptor  Gene Polymorphisms with Bone Mineral Density in Chinese Women: A Meta-Analysis. Osteoporos Int 2007;18(3):295-305 (IF 4.9, Times Cited: 37)
51.  Chen YM, Teucher B, Tang XY, Dainty JR, Lee KK, Woo JL, Ho SC*. Calcium Absorption in Postmenopausal Chinese Women: A Randomized Crossover Intervention Study. Br J Nutr 2007;97(1):160-6.
52.  Chen YM, Ho SC*, Woo JLF. Greater fruit and vegetable intake is associated with increased bone mass among postmenopausal Chinese women. Br J Nutr 2006; 96(4):745-51.  (IF 3.4, Times Cited: 35)
53.  Chen YM, Ho SC*, Lam SS, Chan SS. Validity of body mass index and waist circumference in the classification of obesity as compared to percent body fat in Chinese middle-aged women. Int J Obes  2006; 30(6): 918-925.  (IF 5.1, Times Cited: 18)
54.  Chen YM, Ho SC*. Lam SSH, Ho SSS, Woo JLF. Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial. Menopause 2004; 11(3): 246-254.  (IF 3.1, Times Cited: 43)
55.  Chen YM, Ho SC*, Lam SS, Ho SS, Woo JL. Soy isoflavones have a favorable effect on bone loss in Chinese postmenopausal women with lower bone mass: a double-blind, randomized, controlled trial. J Clin Endocrinol Metab. 2003 Oct; 88(10):4740-4747. (IF 6.3) (Times Cited: 133)

参编教材与论著
1.  陈裕明. 队列研究. 王建华 主编. 流行病学大参考(第一卷)(第三版).
人民卫生出版社. 2015 .
2.  陈裕明. 骨质疏松流行病学. 沈红兵 主编. 流行病学大参考(第三卷)(第三
版).人民卫生出版社。2014.
3.  陈裕明. 第八章 宏量营养素 第一节 钙。中国营养学会 编著. 中国居民膳食
营养素参考摄入量(2013版).科学出版社,2014.10
4.  陈裕明(编委). 预后研究. 沈洪兵 齐秀英 主编. 流行病学. 人民卫生出版社. 2013: pp:114-124. (教材)
5.  刘苑婷 陈裕明. 第七节  蔬菜水果与肿瘤. 石汉平、凌文华、李薇 主编.  肿瘤营养学. 人民卫生出版社 2012
6.  刘苑婷 陈裕明. 第十节 全谷类食物与肿瘤. 石汉平、凌文华、李薇 主编. 肿瘤营养学. 人民卫生出版社 2012
7.  Yu-ming Chen and Suzanne C. Ho. Fruit, Vegetables, and Bone Health. In Ronald Ross Watson and Victor R. Preedy, editors: Bioactive Foods in Promoting Health, Oxford: Academic Press, 2010: pp. 173-194.

研究生与博士后培养、专职科研人员招聘

1.  硕士研究生 每年2-3名 (方向:营养流行病学)
2. 博士研究生 每年1名   (方向:流行病学 或 营养学)
3. 博士后     名额不限  (方向:流行病学 或 营养学)
4. 特聘研究员或副研究员 1-2名
4. MPH和单考班

获奖情况

1. 2013年  中国营养学会营养相关植物化学物优秀科技论文 二等奖 
2. 2008年  中国营养学会第二届营养科技奖 二等奖 (第二名)
3. 2006年  教育部“新世纪优秀人才”
4. 1998年  广东省教育厅、广东省高教厅等  南粤教坛新秀