Guangzhou Municipal Key Laboratory of Environmental Pollution and Health Risk Assessment

Last updated:2016-03-22 22:11:49

The Guangzhou Municipal Key Laboratory of Environmental Pollution and Health Risk Assessment was approved by the Guangzhou Science Technology and Innovation Commission in 2014. To tackle significant global problems in the area of public health and preventive medicine, and to meet the needs of economic and social development of the country and local region at the same time, the Laboratory  focuses on critical environmental pollution problems and food safety problems in the Pearl Delta region and Guangzhou City. Based on basic research, a multidisciplinary approach, and the methods of hybrid exposure of low-dose chemicals and Translational Toxicology, the Laboratory carries out key technology research in population health risk assessment and provides various kinds of public health services for society, including detection analysis of various poisonous chemicals, toxic effect assessment, and measures for disease prevention and control.

The Laboratory has four research orientations as follows:

1.   Mechanism research of environmental chemicals exposure and health damage. Low-dose exposure research using toxicity pathways, basic application research of transgenic animal models, mechanism research of epigenetic, and strategy research of hybrid exposure of low-dose chemicals are included.

2.   Research on exposomics of environmental pollutants. This includes environmental chemical pollutants exposure spectrum analysis technology research; the establishment and development of high-precision analysis techniques; and the systematic screening and identification techniques required to detect illegal food additives.

3.   Verification and evaluation of screened biomarkers in environmental and occupational pollutants within exposed populations. This includes environmental epidemiology investigation; surveillance of exposure biomarkers; detection techniques research of population effect biomarkers; research on biomarkers of hereditary susceptibility; and biomarker detection techniques based on Omics.

4.   Research on risk assessment techniques of computational toxicology based on toxicity pathways. This includes detection of toxicity pathway targets of chemicals and database construction; establishment of dose-response evaluation models based on biological activity; and QSAR model construction based on toxicology pathway analysis and risk assessment techniques research.
Professor Wen Chen, winner of the National Outstanding Youth Science Fund and leader of  the National Key Discipline “Toxicology” of the School of Public Health, Sun Yat-sen University, is in charge of the laboratory. Professor Yun He, Professor Guanghui Dong, Professor Weihua Jia, and Professor Yuantao Hao are the academic leaders. The Laboratory is staffed by an energetic and high-level academic team with a remarkable structure of ages and education backgrounds. There are 15 professors; 12 associate professors and associate senior technicians; and 6 lecturers. Among them, there are two winners of the National Outstanding Youth Science Fund; one Pearl River Scholar; one winner of the Guangdong Pearl River Science Technology New Star award; five teachers selected in the National Thousand-hundred-ten Project; and nine introduced talents in the One Hundred Plan of Sun Yat-sen University.

The Laboratory aspires to the combined principles of openness, progressiveness, and innovation; it strives to possess an international perspective in scientific research. Taking the standards of international management systems for reference, the Laboratory seeks to integrate industry, teaching and scientific research, and to become the leader in Guangdong Province, to demonstrate influence in the country, and to stand at the forefront of international research.

Director, Prof. CHEN Wen, Tel: 8620-87330599, Email: