学术简历


现任中山大学公共卫生学院讲师,硕士生导师。2014年毕业于中山大学中山医学院,获理学博士学位;2015受聘于中山大学公共卫生学院任讲师。致力于病毒感染与免疫分子机制、以及传染病分子流行病学研究。主持国家自然科学基金青年项目1项,中山大学青年教师起步资助计划1项;参与“十二五”国家传染病科技重大专项1项,教育部科学技术研究重大项目1项,国家自然科学基金3项。在国内外杂志发表论文20篇,其中SCI收录文章16篇。以第一作者或并列第一作者在Journal of VirologyJournal of InfectionCellular MicrobiologyPLOS Neglected Tropical DiseasesInternational Journal of Infectious Diseases等杂志发表论著6篇,参与获得发明专利6项。

社会兼职


中华医学会微生物学与免疫学分会会员

主要承担或参与的课题


1. 登革病毒蛋白NS4A参与天然免疫逃逸的功能和分子机制研究 国家自然科学基金 2016/01-2018/12 主持
2. “艾滋病和病毒性肝炎等重大传染病防治”广东省传染病病原谱流行规律研究 国家科技重大专项项目 2012/01-2015/12 参与
3. 登革病毒吸附抑制及虫媒控制防治新策略研究 教育部科学技术研究重大项目 2012/01-2014/12 参与

近期发表的主要文章

1. Zhenjian He, Xun Zhu, Weitao Wen, Jie Yuan, Yiwen Hu, Jiahui Chen, Shu An, Xinhuai Dong, Cuiji Lin, Jianchen Yu, Jueheng Wu, Yi Yang, Junchao Cai, Jun Li, Mengfeng Li *. Dengue virus subverts host innate immunity by targeting adaptor protein MAVS. Journal of Virology. 2016 Jul 27;90(16):7219-7230.
2. Pengyuan Li, Tao Li, Qiuyun Gu, Xiaomin Chen, Jiahui Li, Xiashi Chen, Yan Chen, Danwei Zhang, Rong Gao, Zhenjian He, Xun Zhu, Wangjian Zhang, Yuantao Hao*, Dingmei Zhang*. Children’s Caregivers and Public Playgrounds: Potential Reservoirs of Infection of Hand-foot-and-mouth Disease. Scientific Reports. 2016 Nov 7;6:36375.
3. Weitao Wen #, Zhenjian He #, Qinlong Jing #, Yiwen Hu, Cuiji Lin, Rui Zhou, Xiaoqun Wang, Yangfan Su, Jiehao Yuan, Zhenxin Chen, Jie Yuan, Jueheng Wu, Jun Li, Xun Zhu *, Mengfeng Li *. Cellular microRNA-miR-548g-3p modulates the replication of dengue virus. Journal of Infection. 2015 Jun; 70 (6): 631–640.
4. Xun Zhu #, Zhenjian He #, Jie Yuan #, Weitao Wen, Xuan Huang, Yiwen Hu, Cuiji Lin, Jing Pan, Ran Li, Haijing Deng, Shaowei Liao, Rui Zhou, Jueheng Wu, Jun Li, Mengfeng Li *. IFITM3-containing exosome as a novel mediator for anti-viral response in dengue virus infection. Cellular Microbiology. 2015 Jan;17(1):105-118.
5. Dingmei Zhang #, Mengmeng Ma #, Weitao Wen #, Xun Zhu, Lin Xu, Zhenjian He, Xia He, Jueheng Wu, Yiwen Hu, Yun Zheng, Yu Deng, Cuiji Lin, Jiahai Lu, Mengfeng Li*, Kaiyuan Cao*. Clinical epidemiology and molecular profiling of human bocavirus in faecal samples from children with diarrhoea in Guangzhou, China. Epidemiology and Infection. 2014 Dec; 3:1-15.
6. Xun Zhu #, Zhenjian He #, Yiwen Hu #, Weitao Wen, Cuiji Lin, Jianchen Yu, Jing Pan, Ran Li, Haijing Deng, Shaowei Liao, Jie Yuan, Jueheng Wu, Jun Li, Mengfeng Li *. MicroRNA-30e* Suppresses Dengue Virus Replication by Promoting NF-κB-Dependent IFN Production. PLOS Neglected Tropical Diseases. 2014 Aug 14; 8(8):e3088.
7. Dingmei Zhang #, Zhenjian He#, Lin Xu #, Xun Zhu, Jueheng Wu, Weitao Wen, Yun Zheng, Yu Deng, Jieling Chen, Yiwen Hu, Mengfeng Li *, Kaiyuan Cao *. Epidemiology characteristics of respiratory viruses found in children and adults with respiratory tract infections in southern China. International Journal of Infectious Diseases. 2014 Aug; 25:159-164.
8. Xun Zhu #, Zhenjian He #, Jueheng Wu #, Jie Yuan, Weitao Wen, Yiwen Hu, Yi Jiang, Cuiji Lin, Qianhui Zhang, Min Lin, Henan Zhang, Wan Yang, Hong Chen, Lili Zhong, Zhigang She, Shengping Chen, Yongcheng Lin, Mengfeng Li *. A Marine Anthraquinone SZ-685C Overrides Adriamycin-Resistance in Breast Cancer Cells through Suppressing Akt Signaling. Marine Drugs. 2012 Mar 23; 10 (4): 694-711.
9. Jing Li, Dingmei Zhang, Xun Zhu, Zhenjian He, Shu Liu, Mengfeng Li *, Jiyan Pang *, and Yongcheng Lin *. Studies on Synthesis and Structure-Activity Relationship (SAR) of Derivatives of a New Natural Product from Marine Fungi as Inhibitors of Influenza Virus Neuraminidase. Marine Drugs. 2011 Oct; 9 (10): 1887-901.
10. Xiaofan Ding #, Lifang Jiang #, Changwen Ke #, Zhan Yang, Chunliang Lei, Kaiyuan Cao, Jun Xu, Lin Xu, Xingfen Yang, Yonghui Zhang, Ping Huang, Weijun Huang, Xun Zhu, Zhenjian He, Liping Liu, Jun Li, Jie Yuan, Jueheng Wu, Xiaoping Tang*, Mengfeng Li*. Amino acid sequence analysis and identification of mutations under positive selection in hemagglutinin of 2009 influenza A (H1N1) isolates. Virus Gene. 2010 Dec; 41(3):329-340.
11. 张定梅,朱勋,姚婷婷,徐霖,吴珏珩,何振健,郑芸,曹开源。广东省2009-2012年呼吸道合胞病毒的流行病学特征。中山大学学报(医学科学版),2013 Mar.,34 (2):292-298。