【学位/学历】医学博士
【学习经历】
  2019-08至2023-03 香港中文大学 医学科学（流行病学方向）博士
  2011-09至2019-06 南方医科大学 临床医学 本硕
【工作经历】
  2025-08至今 中山大学公共卫生学院，流行病学系，副教授 ，博士生导师，逸仙学者计划“新锐学者”
  2023-04至2025-04 斯坦福大学 (美国)，博士后研究员
【研究方向及兴趣】
  近年来从事慢性病和代谢性疾病，主要是慢性肝病（尤其是代谢性脂肪肝病）和糖尿病的流行病学和疾病防控的研究，通过开展大数据分析和队列研究，从疾病高危人群识别和筛查，无创诊断方法以及干预和治疗等多角度系统阐明了代谢性疾病的三级预防。主要研究方向为（1）慢性病流行病学，尤其是慢性肝病和代谢性疾病；（2）医学大数据分析；（3）药物治疗及疗效；（4）疾病预测模型（机器学习）。在相关领域国际权威学术期刊已发表科研论文39篇，参与编写2部英文专著，近 5年以通讯/第一作者发表论文19篇，其中发表在中科院1区Top杂志论文 11篇，IF >10的论文8篇。具体以通讯/第一作者在国际权威学术期刊Gut (IF 23.0), Hepatology (3篇, IF 12.9, 其中一篇被选为封面文章), Clinical and Molecular Hepatology (IF 14.0), JAMA Network Open (IF 10.5), Metabolism (IF 10.8), Journal of Advanced Research (IF 11.4), Alimentary pharmacology & therapeutics (2篇, IF 6.6), Hepatobiliary Surgery and Nutrition (IF 6.1), Liver International (IF 6.0), Hepatology Communications (IF 5.6), Journal of Infectious Diseases (IF 5.0)等发表多篇高水平研究论文。其中多项研究成果被纳入国际临床指南并在国际大会进行口头汇报，曾入选“青年研究者奖”和两次荣获“最佳口头报告奖”。以上研究成果获得顶尖学术期刊的多次引用或述评包括JAMA, Nature Reviews Gastroenterology & Hepatology, Journal of Hepatology, Gastroenterology, Gut, Hepatology等。
【论文代表作（近五年）】
1.Zhang X, Sovann Linden, Charlie Robert Gabriel Levesley, Xinyuan He, Zhanpeng Yang, Ramsey Cheung, Fanpu Ji, and Mindie H. Nguyen. Increasing metabolic dysfunction-associated steatotic liver disease mortality and forecast to 2040. JAMA Network Open. 2025 Jun 2;8(6):e2516367. doi: 10.1001/jamanetworkopen.2025.16367. (Impact factor 10.5)
2.Zhou R*, Zhang X*, Liu X, Huang R, Wang Y, Xia D, et al. Association between dietary amino acid intake and the risk of metabolic dysfunction-associated steatotic liver disease. Journal of advanced research. 2025 May 15:S2090-1232(25)00349-2. doi: 10.1016/j.jare.2025.05.029. *Contributed equally to this work (Impact factor 11.4)
3.Zhang X, Mindie H. Nguyen. Metabolic dysfunction-associated steatotic liver disease and breast and gynecological cancers. Metabolism. 2025 Mar 11:167:156190. doi: 10.1016/j.metabol.2025.156190. Online ahead of print. (Impact factor 10.8)
4.Zhang X, Nicholas Rouillard, Xianhua Mao, Rongtao Lai, Ramsey Cheung, Kazunari Sasaki, and Mindie H. Nguyen. Enhanced Long-Term Health with Laparoscopic Bariatric Surgery in Patients with Severe Obesity and Metabolic Dysfunction-Associated Steatotic Liver Disease. Hepatobiliary Surgery and Nutrition. doi:
https://dx.doi.org/10.21037/hbsn-24-529 (Impact factor 6.1)
5.Zhang X, Vy H. Nguyen, Leslie Kam, Scott Barnett, Linda Henry, Ramsey Cheung and Mindie H. Nguyen. Risk stratification of metabolic risk factors and statin use associated with liver and non-liver outcomes in chronic hepatitis B. Journal of Infectious Diseases. 2024 Dec 12:jiae522. doi: 10.1093/infdis/jiae522. Online ahead of print. (Impact factor 5.0)
6.Zhang X, Leslie Kam, Scott Barnett, Linda Henry, Ramsey Cheung and Mindie H. Nguyen. Disease progression for histologic diagnosis of metabolic dysfunction-associated steatotic liver disease in the real-world - a nationwide U.S. study. Digestive Diseases. 2024 Oct 14:1-27. doi: 10.1159/000541945. Online ahead of print.
7.Zhang X, Yip TC, Wong GL, Leow WX, Liang LY, Lim LL, et al. Clinical care pathway to detect advanced liver disease in patients with type 2 diabetes through automated fibrosis score calculation and electronic reminder messages: a randomised controlled trial. Gut. 2023. Aug 7:gutjnl-2023-330269. doi: 10.1136/gutjnl-2023-330269. Online ahead of print. (Impact factor 23.0)
8.Zhang X, Yip TC, Tse YK, Hui VW, Li G, Lin H, et al. Duration of type 2 diabetes and liver-related events in nonalcoholic fatty liver disease: A landmark analysis. Hepatology. 2023. May 1. doi: 10.1097/HEP.0000000000000432. Online ahead of print. (Impact factor 12.9)
9.Zhang X, Wong GL, Yip TC, Cheung TK, Tse YK, Hui VW, et al. Risk of liver-related events by age and diabetes duration in patients with diabetes and non-alcoholic fatty liver disease. Hepatology. 2022 Mar 25. doi: 10.1002/hep.32476. Online ahead of print. (Impact factor 12.9)
10.Zhang X, Wong GL, Yip TC, Tse YK, Liang LY, Hui VW, et al. Angiotensin-converting enzyme inhibitors prevent liver-related events in nonalcoholic fatty liver disease. Hepatology. 2021 Dec 22. doi: 10.1002/hep.32294. Online ahead of print. (Impact factor 12.9) (封面文章)
11.Zhang X, Yip TC, Tse YK, Hui VW, Li G, Lin H, et al. Trends in risk factor control and treatment among patients with non-alcoholic fatty liver disease and type 2 diabetes between 2000 and 2020: A territory-wide study. Alimentary pharmacology & therapeutics. 2023;57(10):1103-16. (Impact factor 6.6)
12.Cheung JTK*, Zhang X*, Wong GL, Yip TC, Lin H, Li G, et al. MAFLD fibrosis score: Using routine measures to identify advanced fibrosis in metabolic-associated fatty liver disease. Alimentary pharmacology & therapeutics. 2023. Sep 19. doi: 10.1111/apt.17722. Online ahead of print. *Contributed equally to this work (Impact factor 6.6)
13.Zhang X, Goh GB, Chan WK, Wong GL, Fan JG, Seto WK, et al. Unhealthy lifestyle habits and physical inactivity among Asian patients with non-alcoholic fatty liver disease. Liver International. 2020 Nov;40:2719-31. doi: 10.1111/liv.14638. (Impact factor 6.0)
14.Zhang X, Wong VW, Yip TC, Tse YK, Liang LY, Hui VW, et al. Colonoscopy and Risk of Colorectal Cancer in Patients With Nonalcoholic Fatty Liver Disease: A Retrospective Territory-Wide Cohort Study. Hepatology Communication. 2021 Mar 21;5(7):1212-1223. doi: 10.1002/hep4.1705. (Impact factor 5.6)
15.Zhang X, Wong GL, Wong VW. Application of transient elastography in nonalcoholic fatty liver disease. Clinical and Molecular Hepatology. 2020 Apr;26:128-41. doi: 10.3350/cmh.2019.0001n. (Impact factor 14.0)
16.Lin H*, Zhang X*, Li G*, Wong GL, Wong VW. Epidemiology and Clinical Outcomes of Metabolic (Dysfunction)-associated Fatty Liver Disease. J Clin Transl Hepatol. 2021;9:972-82. doi: 10.14218/JCTH.2021.00201. *Contributed equally to this work
【研究项目】
2024年度国家重大人才计划青年项目，在研，主持
中山大学“百人计划”引进人才启动经费，主持
【参编教材与论著】
1.Xinrong Zhang, Guanlin Li, Huapeng Lin, Vincent Wai-Sun Wong, Grace Lai-Hung Wong. Noninvasive evaluation of liver fibrosis in MASLD Imaging/elastography based. Metabolic Steatotic Liver Disease. page 151-161. 2024/7/8. Elsevier publisher
2.Xinrong Zhang, Laia Aceituno Sierra, Linda Henry, Mindie H. Nguyen and Arndt Vogel. Liver and Biliary tract cancer. 4th edition of the Textbook of Cancer Epidemiology. Oxford University Press. In progress
【获奖情况】
1.2024 年度 美国消化病周年会 入选研究成果展示奖
2.2022 年度 欧洲肝脏病年会 最佳口头报告奖及Travel Grant奖
3.2021 年度 欧洲肝脏病年会 最佳口头报告奖及Travel Grant奖
4.2020 年度 亚太肝脏病年会 入选青年研究者奖及 Travel Grant奖
【社会兼职】
1.美国肝脏病研究协会委员
2.欧洲肝脏病研究协会委员
3.亚太肝脏病研究协会(代谢性脂肪肝病分委会)委员
4.香港科学协会委员
5.BMC Medicine, Cardiovascular Diabetology, BMC Public Health, BMC Gastroenterology, Digestive Diseases and Sciences, Microbiology Spectrum, Frontiers in Medicine, Frontiers in Endocrinology, Frontiers in Public Health, Nutrients等杂志审稿人
6.Nutrients特刊 “Precision Nutrition: Tailoring Dietary Approaches for Optimal Diabetes Care” 客座主编